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Content DescriptionThis document specifies verification and validation parameters and processes for microarray detection and identification of specific nucleic acid sequences. This document provides recommendations and protocols for: —   microarray design and manufacture; —   validation of hybridization specificity; —   interlaboratory validation of qualitative methods; —   determination of limits of detection for a microarray; —   determination of range of reliable signals; —   criteria for assessing technical performance of the microarray platform: This document is applicable to all methods that use microarrays for detection of nucleic acids. It does not apply to the following protocols: —   quantitative measurement; —   requirements for sample preparation prior to DNA microarray experiments. About ISOISO, the International Organization for Standardization, brings global experts together to agree on the best way of doing things – for anything from making a product to managing a process. As one of the oldest non-governmental international organizations, ISO has enabled trade and cooperation between people and companies all over the world since 1946. The International Standards published by ISO serve to make lives easier, safer and better. |
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